tourette's+syndrom

__Gilles de la Tourette's syndrome [] __  Type of genetic disorder: Tourettes is a genetic disorder that is believed to be inherited through a gene. The gene has been identified in small number of people with Tourette's syndrome as a mutation of the SLITRK1 gene, but this does not apply to all. Other factors make it more likely to develop such as, emotional and physical health or external stress. The Tourettes gene is dominant, but may not appear in the children. The children instead may display another tic disorder or obsessive compulsive disorder. The sex of a child has an ifluence on the chance of inheriting Tourettes. Males are three times more likely than females to inherit the disorder, however the gene is not sex linked.

Tourette syndrome is a complex disorder characterized by repetitive, sudden, and involuntary movements or noises called tics. Tics usually appear in childhood, and their severity varies over time. In most cases, tics become milder and less frequent in late adolescence and adulthood. Tourette syndrome involves both motor tics, which are uncontrolled body movements, and vocal or phonic tics, which are outbursts of sound. Some motor tics are simple and involve only one muscle group. Simple motor tics, such as rapid eye blinking, shoulder shrugging, or nose twitching, are usually the first signs of Tourette syndrome. Motor tics also can be complex (involving multiple muscle groups), such as jumping, kicking, hopping, or spinning. Vocal tics, which generally appear later than motor tics, also can be simple or complex. Simple vocal tics include grunting, sniffing, and throat-clearing. More complex vocalizations include repeating the words of others or repeating one's own words. The involuntary use of inappropriate or obscene language is possible, but uncommon, among people with Tourette syndrome. [] Generally, TS is diagnosed by obtaining a description of the tics and evaluating family history. For a diagnosis of TS to be made, both motor and phonic tics must be present for at least 1 year. Neuroimaging studies, such as magnetic resonance imaging (MRI), computerized tomography (CT), and electroencephalogram (EEG) scans, or certain blood tests may be used to rule out other conditions that might be confused with TS. However, TS is a clinical diagnosis. There are no blood tests or other laboratory tests that definitively diagnose the disorder.
 * Description **
 * Diagnosis: **

The prognosis for Tourette syndrome in individuals without associated psychological conditions is often quite good, and only approximately 10% of Tourette syndrome individuals experience severe tic symptoms. Approximately 30% of people with Tourette syndrome will experience a decrease in the frequency and severity of tics, and another 30–40% will experience a complete end of symptoms by late adolescence. The other 30–40% will continue to exhibit moderate to severe symptoms in adulthood. There does not appear to be a definite correlation between the type, frequency, and severity of symptoms and the eventual prognosis. Patients with severe tics may experience social difficulties and may isolate themselves from others in fear of shocking and embarrassing them. People with Tourette syndrome who have such other symptoms as obsessive compulsive disorder, attention deficit disorder, and self-injurious behavior usually have a poorer prognosis. []
 * Prognosis: **
 * [[image:http://tbn2.google.com/images?q=tbn:PyuqSYASKdw9rM:http://cdn-write.demandstudios.com/upload//9000/700/80/6/49786_125x175_aspect.jpg width="114" height="136" caption="See full size image" link="http://cdn-write.demandstudios.com/upload//9000/700/80/6/49786_125x175_aspect.jpg"]]

Treatment: ** People with life-disrupting symptoms can often suppress them with one of several drugs that affect the chemistry of the brain, including haloperidol, clonidine, pimozide, fluphenazine, clomipramine, and fluoxetine. However, the medications have side effects that themselves can be life-disrupting, like somnolence, and some people with Tourette's refuse medication, finding its symptoms less troublesome than those caused by drugs. [] Between 1 to 10 in a 1000 children have Tourette’s syndrome, but most only display mild non-debilitating symptoms.
 * Statistics: **

About 50% of children with Tourette’s will lose their tics in late adolescence

Only twelve percent of children with Tourette’s only display have it and no other disorders. Eight-eight percent of the other children will display another disorder like ADHD, OCD, trouble sleeping, rage attacks, anxiety and depression

TS is three to four times more common in boys than girls

Only 10% of children with Tourettes display coprolalia or the shouting of obscene language involuntarily. [] [] [] []
 * Other Info :**famous people with tourette’s syndrome include, Tim Howard, Howard Hughes, Howie Mandel, Dan Ackroyd, David Beckham, and Michael Wolff.
 * Sources ** [|**http://neurology.health-cares.net/tourettes-syndrome-causes.php**]

RJS- Great job, you have got a lot of good information, I did not realize that most tourettes victims lost their tics. Good information but you don't have any pictures yet. Pictures worths 12 easy POINTS. Don't screw this up (Cri-Du-Chat, LN) Explain what Giles de la Tourretes means. (HG-Huntington's)

